Cardiac fibroblast transcriptome analyses support a role for interferogenic, profibrotic, and inflammatory genes in anti-SSA/Ro-associated congenital heart block

Clancy, RM; Markham, AJ; Jackson, T; Rasmussen, SE; Blumenberg, M; Buyon, JP

Clancy, RM (reprint author), NYU, Div Rheumatol, Dept Med, Langone Med Ctr, 550 First Ave,Med Sci Bldg 609, New York, NY 10016 USA.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2017; 313 (3): H631

Abstract

The signature lesion of SSA/Ro autoantibody-associated congenital heart block (CHB) is fibrosis and a macrophage infiltrate, supporting an experimenta......

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