Metabolically distinct roles of NAD synthetase and NAD kinase define the essentiality of NAD and NADP in Mycobacterium tuberculosis

Sharma, R; Hartman, TE; Beites, T; Kim, JH; Eoh, H; Engelhart, CA; Zhu, LN; Wilson, DJ; Aldrich, CC; Ehrt, S; Rhee, KY; Schnappinger, D

Schnappinger, D (通讯作者)，Weill Cornell Med Coll, Dept Microbiol & Immunol, New York, NY 10065 USA.;Rhee, KY (通讯作者)，Weill Cornell Med Coll, Dept Med, New York, NY 10065 USA.

MBIO, 2023; 14 (4):

Abstract

The current course for cure of Mycobacterium tuberculosis (Mtb)-the etiologic agent of tuberculosis (TB)-infections is lengthy and requires multiple a......

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