Endothelial cell-derived tetrahydrobiopterin prevents aortic valve calcification

Liu, ZT; Dong, NG; Hui, HP; Wang, YX; Liu, FY; Xu, L; Liu, M; Rao, ZQ; Yuan, Z; Shang, YQ; Feng, J; Cai, ZJ; Li, F

Li, F (通讯作者)，Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Dept Cardiovasc Surg, 1277 Jiefang Ave, Wuhan 430022, Hubei, Peoples R China.;Cai, ZJ (通讯作者)，Zhejiang Univ, Affiliated Hosp 2, Dept Cardiol, Sch Med, 88 Jiefang Rd, Hangzhou 310009, Zhejiang, Peoples R China.

EUROPEAN HEART JOURNAL, 2022; 43 (17): 1652

Abstract

Aims Tetrahydrobiopterin (BH4) is a critical determinant of the biological function of endothelial nitric oxide synthase. The present study was to inv......

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