The ubiquitin ligase STUB1 regulates stability and activity of RUNX1 and RUNX1-RUNX1T1

Yonezawa, T; Takahashi, H; Shikata, S; Liu, XX; Tamura, M; Asada, S; Fukushima, T; Fukuyama, T; Tanaka, Y; Sawasaki, T; Kitamura, T; Goyama, S

Goyama, S (reprint author), Univ Tokyo, Inst Med Sci, Div Cellular Therapy, Minato Ku, 4-6-1 Shirokanedai, Tokyo 1088639, Japan.

JOURNAL OF BIOLOGICAL CHEMISTRY, 2017; 292 (30): 12528

Abstract

RUNX1 is a member of RUNX transcription factors and plays important roles in hematopoiesis. Disruption of RUNX1 activity has been implicated in the de......

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