Purification and structure of luminal domain C of human Niemann-Pick C1 protein

Odongo, L; Zadrozny, KK; Diehl, WE; Luban, J; White, JM; Ganser-Pornillos, BK; Tamm, LK; Pornillos, O

Tamm, LK (通讯作者)，Univ Virginia, Ctr Membrane & Cell Physiol, Charlottesville, VA 22908 USA.;Tamm, LK (通讯作者)，Univ Virginia, Dept Mol Physiol & Biol Phys, Charlottesville, VA 22908 USA.

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 2023; 79 (): 45

Abstract

Niemann-Pick C1 protein (NPC1) is a membrane protein that primarily resides in late endosomes and lysosomes, and plays an important role in cholestero......

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