Evolocumab in Pediatric Heterozygous Familial Hypercholesterolemia

Santos, RD; Ruzza, A; Hovingh, GK; Wiegman, A; Mach, F; Kurtz, CE; Hamer, A; Bridges, I; Bartuli, A; Bergeron, J; Szamosi, T; Santra, S; Stefanutti, C; Descamps, OS; Greber-Platzer, S; Luirink, I; Kastelein, JJP; Gaudet, D

Gaudet, D (corresponding author), Univ Montreal, Dept Med, 930 Jacques Cartier, Chicoutimi, PQ G7H 7K9, Canada.; Gaudet, D (corresponding author), ECOGENE 21 Clin Res Ctr, 930 Jacques Cartier, Chicoutimi, PQ G7H 7K9, Canada.; Santos, RD (corresponding author), Univ Sao Paulo, Med Sch Hosp, Lipid Clin Heart Inst, BR-05403900 Sao Paulo, Brazil.; Santos, RD (corresponding author), Hosp Israelita Albert Einstein, BR-05403900 Sao Paulo, Brazil.

NEW ENGLAND JOURNAL OF MEDICINE, 2020; 383 (14): 1317

Abstract

BackgroundEvolocumab, a fully human monoclonal antibody directed against proprotein convertase subtilisin-kexin type 9, is widely used in adult patien......

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