Fc gamma R Binding and ADCC Activity of Human IgG Allotypes

de Taeye, SW; Bentlage, AEH; Mebius, MM; Meesters, JI; Lissenberg-Thunnissen, S; Falck, D; Senard, T; Salehi, N; Wuhrer, M; Schuurman, J; Labrijn, AF; Rispens, T; Vidarsson, G

de Taeye, SW (corresponding author), Univ Amsterdam, Dept Immunopathol, Sanquin Res & Landsteiner Lab, Amsterdam UMC, Amsterdam, Netherlands.; de Taeye, SW (corresponding author), Univ Amsterdam, Dept Expt Immunohematol, Sanquin Res & Landsteiner Lab, Amsterdam UMC, Amsterdam, Netherlands.; de Taeye, SW (corresponding author), Univ Amsterdam, Dept Med Microbiol, Amsterdam UMC, Amsterdam, Netherlands.

FRONTIERS IN IMMUNOLOGY, 2020; 11 ():

Abstract

Antibody dependent cellular cytotoxicity (ADCC) is an Fc-dependent effector function of IgG important for anti-viral immunity and anti-tumor therapies......

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