An enhanced antioxidant strategy of astaxanthin encapsulated in ROS-responsive nanoparticles for combating cisplatin-induced ototoxicity

Gu, JY; Wang, XL; Chen, YM; Xu, K; Yu, DH; Wu, H

Yu, DH (通讯作者),Shanghai Jiao Tong Univ, Sch Med, Peoples Hosp 9, Dept Otolaryngol Head & Neck Surg, Shanghai, Peoples R China.;Yu, DH (通讯作者),Shanghai Jiao Tong Univ, Sch Med, Ear Inst, Shanghai, Peoples R China.;Yu, DH (通讯作者),Shanghai Key Lab Translat Med Ear & Nose Dis 14DZ, Shanghai, Peoples R China.;Yu, DH (通讯作者),Shanghai Univ, Sch Life Sci, Materdicine Lab, Shanghai, Peoples R China.

JOURNAL OF NANOBIOTECHNOLOGY, 2022; 20 (1):

Abstract

Background: Excessive accumulation of reactive oxygen species (ROS) has been documented as the crucial cellular mechanism of cisplatin-induced ototoxi......

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