Synthesis of 2'-modified N6-methyladenosine phosphoramidites and their incorporation into siRNA

Rydzik, AM; Riether, D; Gottschling, D

Rydzik, AM (通讯作者)，Boehringer Ingelheim Pharm GmbH & Co KG, Biberach, Germany.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023; 81 ():

Abstract

A synthesis of 2 '-fluoro and 2 '-methoxy N6-methyladenosine phosphoramidites and their successful incorpora-tion into oligonucleotides is reported. 2......

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