The Ketosynthase Domain Controls Chain Length in Mushroom Oligocyclic Polyketide Synthases

Löhr, NA; Urban, MC; Eisen, F; Platz, L; Hüttel, W; Gressler, M; Müller, M; Hoffmeister, D

Hoffmeister, D (通讯作者)，Friedrich Schiller Univ, Hans Knoll Inst, Dept Pharmaceut Microbiol, Beutenbergstr 11a, D-07745 Jena, Germany.

CHEMBIOCHEM, 2023; 24 (3):

Abstract

The nonreducing iterative type I polyketide synthases (NR-PKSs) CoPKS1 and CoPKS4 of the webcap mushroom Cortinarius odorifer share 88 % identical ami......

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