Catalytic mechanism of the mismatch-specific DNA glycosylase methyl-CpG-binding domain 4

Ouzon-Shubeita, H; Jung, H; Lee, MH; Koag, MC; Lee, S

Lee, S (corresponding author), Univ Texas Austin, Coll Pharm, Div Chem Biol & Med Chem, Austin, TX 78712 USA.

BIOCHEMICAL JOURNAL, 2020; 477 (9): 1601

Abstract

Thymine:guanine base pairs are major promutagenic mismatches occurring in DNA metabolism. If left unrepaired, these mispairs can cause C to T transiti......

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