CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells

Kurt, IC; Zhou, RH; Iyer, S; Garcia, SP; Miller, BR; Langner, LM; Grunewald, J; Joung, JK

Grunewald, J; Joung, JK (corresponding author), Massachusetts Gen Hosp, Mol Pathol Unit, Charlestown, MA 02129 USA.; Grunewald, J; Joung, JK (corresponding author), Massachusetts Gen Hosp, Ctr Canc Res, Charlestown, MA 02129 USA.; Grunewald, J; Joung, JK (corresponding author), Massachusetts Gen Hosp, Ctr Computat & Integrat Biol, Charlestown, MA 02129 USA.; Grunewald, J; Joung, JK (corresponding author), Harvard Med Sch, Dept Pathol, Boston, MA 02115 USA.

NATURE BIOTECHNOLOGY, 2021; 39 (1): 41

Abstract

CRISPR-guided DNA cytosine and adenine base editors are widely used for many applications(1-4)but primarily create DNA base transitions (that is, pyri......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索