TET2 exon 2 skipping is an independent favorable prognostic factor for cytogenetically normal acute myelogenous leukemia (AML) TET2 exon 2 skipping in AML

Mohamed, AM; Balsat, M; Koering, C; Maucort-Boulch, D; Boissel, N; Payen-Gay, L; Cheok, M; Mortada, H; Auboeuf, D; Pinatel, C; El-Hamri, M; Tigaud, I; Hayette, S; Dumontet, C; Cros, E; Flandrin-Gresta, P; Nibourel, O; Preudhomme, C; Thomas, X; Nicoli

Mortreux, F; Wattel, E (reprint author), Univ Lyon 1, ENS HCL, CNRS UMR5239, Fac Med Lyon Sud,Oncovirol & Biotherapies, Pierre Benite, France.

LEUKEMIA RESEARCH, 2017; 56 ( ): 21

Abstract

In AML, approximately one-third of expressed genes are abnormally spliced, including aberrant TET2 exon 2 expression. In a discovery cohort (n=99), TE......

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