SLIT2 promoter hypermethylation-mediated SLIT2-IT1/miR-218 repression drives leukemogenesis and predicts adverse prognosis in myelodysplastic neoplasm

Zhang, TJ; Xu, ZJ; Wen, XM; Gu, Y; Ma, JC; Yuan, Q; Lin, J; Zhou, JD; Qian, J

Zhou, JD; Qian, J (通讯作者)，Jiangsu Univ, Dept Hematol, Affiliated Peoples Hosp, Zhenjiang 212002, Jiangsu, Peoples R China.;Lin, J; Zhou, JD; Qian, J (通讯作者)，Zhenjiang Clin Res Ctr Hematol, Zhenjiang 212002, Jiangsu, Peoples R China.;Lin, J; Zhou, JD; Qian, J (通讯作者)，Key Lab Precis Diag & Treatment Hematol Malignanc, Zhenjiang 212002, Jiangsu, Peoples R China.;Lin, J (通讯作者)，Jiangsu Univ, Lab Ctr, Affiliated Peoples Hosp, Zhenjiang 212002, Jiangsu, Peoples R China.

LEUKEMIA, 2022; 36 (10): 2488

Abstract

Epigenetic modifications have been found to play crucial roles in myelodysplastic neoplasm (MDS) progression. Previously, we investigated genome-wide ......

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