Familial ALS-associated SFPQ variants promote the formation of SFPQ cytoplasmic aggregates in primary neurons

Widagdo, J; Udagedara, S; Bhembre, N; Tan, JZA; Neureiter, L; Huang, J; Anggono, V; Lee, MH

Anggono, V (通讯作者),Univ Queensland, Queensland Brain Inst, Clem Jones Ctr Ageing Dementia Res, Brisbane, Qld 4072, Australia.;Lee, MH (通讯作者),La Trobe Univ, La Trobe Inst Mol Sci, Dept Biochem & Chem, Melbourne, Vic 3086, Australia.

OPEN BIOLOGY, 2022; 12 (9):

Abstract

Splicing factor proline- and glutamine-rich (SFPQ) is a nuclear RNA-binding protein that is involved in a wide range of physiological processes includ......

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