NINJ1 mediates plasma membrane rupture during lytic cell death

Kayagaki, N; Kornfeld, OS; Lee, BL; Stowe, IB; O'Rourke, K; Li, QL; Sandoval, W; Yan, DH; Kang, J; Xu, M; Zhang, J; Lee, WP; McKenzie, BS; Ulas, G; Payandeh, J; Roose-Girma, M; Modrusan, Z; Reja, R; Sagolla, M; Webster, JD; Cho, V; Andrews, TD; Morris, LX; Miosge, LA; Goodnow, CC; Bertram, EM; Dixit, VM

Kayagaki, N; Dixit, VM (corresponding author), Genentech Inc, Dept Physiol Chem, San Francisco, CA 94080 USA.

NATURE, ; ():

Abstract

The small transmembrane protein NINJ1 promotes plasma membrane rupture in lytic cell death associated with pyroptosis, necrosis and apoptosis. Plasma ......

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