?Np63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells

Lambert, AW; Fiore, C; Chutake, Y; Verhaar, ER; Strasser, PC; Chen, MW; Farouq, D; Das, S; Li, X; Eaton, EN; Zhang, Y; Donaher, JL; Engstrom, I; Reinhardt, F; Yuan, BB; Gupta, S; Wollison, B; Eaton, M; Bierie, B; Carulli, J; Olson, ER; Guenther, MG; Weinberg, RA

Weinberg, RA (通讯作者)，Whitehead Inst Biomed Res, Cambridge, MA 02142 USA.;Weinberg, RA (通讯作者)，MIT, Dept Biol, Cambridge, MA 02142 USA.;Weinberg, RA (通讯作者)，Ludwig Ctr Mol Oncol, Cambridge, MA 02139 USA.

DEVELOPMENTAL CELL, 2022; 57 (24): 2714

Abstract

Cancer stem cells (CSCs) may serve as the cellular seeds of tumor recurrence and metastasis, and they can be generated via epithelial-mesenchymal tran......

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