Exosomes induce endolysosomal permeabilization as a gateway by which exosomal tau seeds escape into the cytosol-MedSci.cn

Exosomes induce endolysosomal permeabilization as a gateway by which exosomal tau seeds escape into the cytosol

Polanco, JC; Hand, GR; Briner, A; Li, CZ; Gotz, J

Polanco, JC; Gotz, J (corresponding author), Univ Queensland, Queensland Brain Inst QBI, Clem Jones Ctr Ageing Dementia Res CJCADR, Brisbane, Qld 4072, Australia.

ACTA NEUROPATHOLOGICA, 2021; 141 (2): 235

Abstract

The microtubule-associated protein tau has a critical role in Alzheimer's disease and other tauopathies. A proposed pathomechanism in the progression ......

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