Defective IGF-1 prohormone N-glycosylation and reduced IGF-1 receptor signaling activation in congenital disorders of glycosylation

Di Patria, L; Annibalini, G; Morrone, A; Ferri, L; Saltarelli, R; Galluzzi, L; Diotallevi, A; Bocconcelli, M; Donati, MA; Barone, R; Guerrini, R; Jaeken, J; Stocchi, V; Barbieri, E

Annibalini, G (通讯作者)，Univ Urbino Carlo Bo, Dept Biomol Sci, Via I Maggetti 26-2, I-61029 Urbino, Italy.

CELLULAR AND MOLECULAR LIFE SCIENCES, 2022; 79 (3):

Abstract

The insulin-like growth factor-1 (IGF-1) signaling pathway is crucial for the regulation of growth and development. The correct processing of the IGF-......

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