IL13Rα2-targeted third-generation CAR-T cells with CD28 transmembrane domain mediate the best anti-glioblastoma efficacy

Gu, AQ; Bai, Y; Zhang, C; Xu, C; An, ZJ; Zhang, Y; Zhong, SH; Hu, Y; Zhong, XS

Hu, Y; Zhong, XS (通讯作者)，Capital Med Univ, Beijing Shijitan Hosp, Clin Ctr Gene & Cell Engn, 10 Iron Med Rd, Beijing 100038, Peoples R China.;Zhong, XS (通讯作者)，Carriage Therapeut Affiliat, Beijing, Peoples R China.

CANCER IMMUNOLOGY IMMUNOTHERAPY, 2023; 72 (7): 2393

Abstract

Chimeric antigen receptor (CAR)-modified T (CAR-T) cell therapy has been proven to be a powerful tool for the treatment of cancer, however, the limits......

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