Cyclin J-CDK complexes limit innate immune responses by reducing proinflammatory changes in macrophage metabolism

Chong, YK; Tartey, S; Yoshikawa, Y; Imami, K; Li, SL; Yoshinaga, M; Hirabayashi, A; Liu, GH; Vandenbon, A; Hia, F; Uehata, T; Mino, T; Suzuki, Y; Noda, T; Ferrandon, D; Standley, DM; Ishihama, Y; Takeuchi, O

Takeuchi, O (通讯作者)，Kyoto Univ, Grad Sch Med, Dept Med Chem, Kyoto, Japan.

SCIENCE SIGNALING, 2022; 15 (729):

Abstract

Toll-like receptor (TLR) stimulation induces glycolysis and the production of mitochondrial reactive oxygen species (ROS), both of which are critical ......

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