RIPK1 Promotes Energy Sensing by the mTORC1 Pathway

Najafov, A; Luu, HS; Mookhtiar, AK; Mifflin, L; Xia, HG; Amin, PP; Ordureau, A; Wang, HB; Yuan, JY

Najafov, A; Yuan, JY (corresponding author), Harvard Med Sch, Dept Cell Biol, Boston, MA 02115 USA.; Najafov, A; Yuan, JY (corresponding author), Harvard Med Sch, Ludwig Ctr, Boston, MA 02115 USA.

MOLECULAR CELL, 2021; 81 (2): 370

Abstract

The mechanisms of cellular energy sensing and AMPK-mediated mTORC1 inhibition are not fully delineated. Here, we discover that RIPK1 promotes mTORC1 i......

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