The m6A methyltransferase Mettl3 deficiency attenuates hepatic stellate cell activation and liver fibrosis

Li, YL; Kang, XM; Zhou, ZW; Pan, LJ; Chen, HX; Liang, XQ; Chu, JJ; Dong, S; Liu, C; Yu, SS; Tu, D; Zhang, YW; Ge, M; Chen, WJ; Xu, Y; Zhang, Q

Xu, Y; Zhang, Q (通讯作者)，Sun Yat Sen Univ, Affiliated Hosp 3, Biotherapy Ctr, Guangzhou, Peoples R China.;Xu, Y; Zhang, Q (通讯作者)，Sun Yat Sen Univ, Affiliated Hosp 3, Biotherapy Ctr, 600 Tianhe Rd, Guangzhou 510630, Peoples R China.

MOLECULAR THERAPY, 2022; 30 (12): 3714

Abstract

Activation of hepatic stellate cells (HSCs) is a central driver of liver fibrosis. Previous investigations have identified various altered epigenetic ......

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