Structural dissection of amyloid aggregates of TDP-43 and its C-terminal fragments TDP-35 and TDP-16

Shenoy, J; El Mammeri, N; Dutour, A; Berbon, M; Saad, A; Lends, A; Morvan, E; Grelard, A; Lecomte, S; Kauffmann, B; Theillet, FX; Habenstein, B; Loquet, A

Habenstein, B; Loquet, A (reprint author), Univ Bordeaux, CNRS, Inst Europeen Chim & Biol, IPB,CBMN,UMR5248, 2 Rue Escarpit, Pessac, France.

FEBS JOURNAL, 0; ():

Abstract

The TAR DNA-binding protein (TDP-43) self-assembles into prion-like aggregates considered to be the structural hallmark of amyotrophic lateral scleros......

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