Synthesis and biological evaluation of novel steroidal 5 alpha,8 alpha-epidioxyandrost-6-ene-3 beta-ol-17-(O-phenylacetamide)oxime derivatives as potential anticancer agents

Bu, M; Cao, TT; Li, HX; Guo, MZ; Yang, BB; Zeng, CC; Zhou, Y; Zhang, N; Hu, LM

Hu, LM (reprint author), Beijing Univ Technol, Coll Life Sci & Bioengn, Dept Biomed Engn, Beijing 100124, Peoples R China.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017; 27 (16): 3856

Abstract

Inspired by the significant anti-cancer activity of our previously screened natural ergosterol peroxide (EP, 1), we synthesized and characterized a se......

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