Pharmacokinetics of Herb-Drug Interactions of Plumbagin and Tazemetostat in Rats by UPLC-MS/MS

Li, H; Wang, YJ; Geng, XN; Kang, YR; Wang, YL; Qiu, XJ

Qiu, XJ (通讯作者)，Henan Univ Sci & Technol, Sch Basic Med Sci, Dept Pharm, Luoyang 471023, Peoples R China.;Qiu, XJ (通讯作者)，Henan Univ Sci & Technol, Funct Expt Teaching Ctr, Sch Basic Med Sci, 263 Kaiyuan Ave, Luoyang 471023, Henan, Peoples R China.

DRUG DESIGN DEVELOPMENT AND THERAPY, 2022; 16 (): 3385

Abstract

Objective: A sensitive and rapid UPLC-MS/MS method for determination of tazemetostat in rat plasma was developed, and the pharmacokinetics of herb-dru......

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