A precision therapy against cancers driven by KIT/PDGFRA mutations

Evans, EK; Gardino, AK; Kim, JL; Hodous, BL; Shutes, A; Davis, A; Zhu, XJ; Schmidt-Kittler, O; Wilson, D; Wilson, K; DiPietro, L; Zhang, YL; Brooijmans, N; LaBranche, TP; Wozniak, A; Gebreyohannes, YK; Schoffski, P; Heinrich, MC; DeAngelo, DJ; Miller

Lengauer, C (reprint author), Blueprint Med, Cambridge, MA 02139 USA.

SCIENCE TRANSLATIONAL MEDICINE, 2017; 9 (414):

Abstract

Targeting oncogenic kinase drivers with small-molecule inhibitors can have marked therapeutic benefit, especially when administered to an appropriate ......

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