Gain-of-function mutations in granulocyte colony-stimulating factor receptor (CSF3R) reveal distinct mechanisms of CSF3R activation

Zhang, HJ; Coblentz, C; Watanabe-Smith, K; Means, S; Means, J; Maxson, JE; Tyner, JW

Maxson, JE (reprint author), Oregon Hlth & Sci Univ, Div Hematol & Med Oncol, Knight Canc Inst, 3181 SW Sam Jackson Pk Rd,BRB 553,Mailcode L592, Portland, OR 97239 USA.; Tyner, JW (reprint author), Oregon Hlth & Sci Univ, Knight Canc Inst, 3181 SW Sam Jac

JOURNAL OF BIOLOGICAL CHEMISTRY, 2018; 293 (19): 7387

Abstract

Granulocyte colony-stimulating factor (G-CSF or CSF3) and its receptor CSF3R regulate granulopoiesis, neutrophil function, and hematopoietic stem cell......

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