Glucolipotoxicity induces endothelial cell dysfunction by activating autophagy and inhibiting autophagic flow

Liu, YL; Xiang, H; Xiong, WF; Ouyang, J; Liu, HD; Zhao, SL; Xiao, J; Li, JL; Shu, ZH; Wang, XW; Liu, HQ; Zhang, J; Fan, JI; Li, Y; Chen, SH; Lu, HW

Lu, HW (通讯作者)，Cent South Univ, Xiangya Hosp 3, Ctr Expt Med, 138 Tongzipo Rd, Changsha 410013, Peoples R China.;Chen, SH (通讯作者)，Cent South Univ, Sch Life Sci, Dept Biochem, 172 Tongzipo Rd, Changsha 410013, Peoples R China.

DIABETES & VASCULAR DISEASE RESEARCH, 2022; 19 (3):

Abstract

Objectives This study aims to determine the role and mechanism of autophagy in endothelial cell dysfunction by glucolipotoxicity. Methods Human umbili......

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