G-Quadruplex loops regulate PARP-1 enzymatic activation

Edwards, AD; Marecki, JC; Byrd, AK; Gao, J; Raney, KD

Raney, KD (corresponding author), Univ Arkansas Med Sci, Dept Biochem & Mol Biol, Little Rock, AR 72205 USA.; Raney, KD (corresponding author), Univ Arkansas Med Sci, Winthrop P Rockefeller Canc Inst, Little Rock, AR 72205 USA.

NUCLEIC ACIDS RESEARCH, 2021; 49 (1): 416

Abstract

G-Quadruplexes are non-B form DNA structures present at regulatory regions in the genome, such as promoters of proto-oncogenes and telomeres. The prom......

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