Sparse deconvolution improves the resolution of live-cell super-resolution fluorescence microscopy

Zhao, WS; Zhao, SQ; Li, LJ; Huang, XS; Xing, SJ; Zhang, YL; Qiu, GH; Han, ZQ; Shang, YX; Sun, DE; Shan, CY; Wu, RL; Gu, LS; Zhang, SW; Chen, RW; Xiao, J; Mo, YQ; Wang, JY; Ji, W; Chen, X; Ding, BQ; Liu, YM; Mao, H; Song, BL; Tan, JB; Liu, J; Li, HY; Chen, LY

Li, HY (通讯作者),Harbin Inst Technol, Sch Instrumentat Sci & Engn, Adv Microscopy & Instrumentat Res Ctr, Harbin, Peoples R China.;Chen, LY (通讯作者),Peking Univ, State Key Lab Membrane Biol, Beijing Key Lab Cardiometab Mol Med, Inst Mol Med,Sch Future Technol,Natl Biomed Imagi, Beijing, Peoples R China.;Li, HY (通讯作者),Harbin Inst Technol, Key Lab Ultraprecis Intelligent Instrumentat, Minist Ind & Informat Technol, Harbin, Peoples R China.;Li, HY (通讯作者),Harbin Inst Technol, Lab Space Environm & Phys Sc

NATURE BIOTECHNOLOGY, 2022; 40 (4): 606

Abstract

A main determinant of the spatial resolution of live-cell super-resolution (SR) microscopes is the maximum photon flux that can be collected. To furth......

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