Misfolded SOD1 is not a primary component of sporadic ALS

Da Cruz, S; Bui, A; Saberi, S; Lee, SK; Stauffer, J; McAlonis-Downes, M; Schulte, D; Pizzo, DP; Parone, PA; Cleveland, DW; Ravits, J

Cleveland, DW (reprint author), Univ Calif San Diego, Ludwig Inst Canc Res, Cell Biol Lab, 9500 Gilman Dr, La Jolla, CA 92093 USA.; Cleveland, DW (reprint author), Univ Calif San Diego, Dept Cellular & Mol Med, 9500 Gilman Dr, La Jolla, CA 92093 USA.; Cle

ACTA NEUROPATHOLOGICA, 2017; 134 (1): 97

Abstract

A common feature of inherited and sporadic ALS is accumulation of abnormal proteinaceous inclusions in motor neurons and glia. SOD1 is the major prote......

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