Endothelium-protective, histone-neutralizing properties of the polyanionic agent defibrotide

Shi, H; Gandhi, AA; Smith, SA; Wang, QY; Chiang, D; Yalavarthi, S; Ali, RA; Liu, C; Sule, G; Tsou, PS; Zuo, Y; Kanthi, Y; Farkash, EA; Lin, JD; Morrissey, JH; Knight, JS

Knight, JS (corresponding author), 1150 West Med Ctr Dr, Ann Arbor, MI 48109 USA.

JCI INSIGHT, 2021; 6 (17):

Abstract

Neutrophil-mediated activation and injury of the endothelium play roles in the pathogenesis of diverse disease states ranging from autoimmunity to can......

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