Novel site-specific PEGylated L-asparaginase

Meneguetti, GP; Santos, JHPM; Obreque, KMT; Barbosa, CMV; Monteiro, G; Farsky, SHP; de Oliveira, AM; Angeli, CB; Palmisano, G; Ventura, SPM; Pessoa, A; Rangel-Yagui, CD

Rangel-Yagui, CD (reprint author), Univ Sao Paulo, Dept Biochem & Pharmaceut Technol, Sao Paulo, Brazil.

PLOS ONE, 2019; 14 (2):

Abstract

L-asparaginase (ASNase) from Escherichia coli is currently used in some countries in its PEGylated form (ONCASPAR, pegaspargase) to treat acute lympho......

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