UBE2O promotes the proliferation, EMT and stemness properties of breast cancer cells through the UBE2O/AMPK alpha 2/mTORC1-MYC positive feedback loop

Liu, X; Ma, F; Liu, CX; YZhu, KY; Li, WJ; Xu, YT; Li, G; Niu, ZB; Liu, JX; Chen, D; Li, ZG; Fu, YQ; Qian, C

Qian, C (corresponding author), Harbin Med Univ, Canc Hosp, Dept Breast Canc Surg, Harbin, Heilongjiang, Peoples R China.; Qian, C (corresponding author), Harbin Med Univ, North China Translat Med Res Ctr, Harbin, Heilongjiang, Peoples R China.

CELL DEATH & DISEASE, 2020; 11 (1):

Abstract

Ubiquitin-conjugating enzyme E2O (UBE2O) is a large E2 ubiquitin-conjugating enzyme that possesses both E2 and E3 ligase activities. Ectopic UBE2O ove......

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