Radiosynthesis and preclinical evaluation of [11C]SNX-ab as an Hsp90α,β isoform-selective PET probe for in vivo brain and tumour imaging

Cools, R; Vermeulen, K; Narykina, V; Leitao, RCF; Bormans, G

Bormans, G (通讯作者),Katholieke Univ Leuven, Lab Radiopharmaceut Res, Dept Pharmaceut & Pharmacol Sci, B-3000 Leuven, Belgium.

EJNMMI RADIOPHARMACY AND CHEMISTRY, 2023; 8 (1):

Abstract

Background The molecular chaperone, Hsp90, is a key player in the protein quality control system that maintains homeostasis under cellular stress cond......

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