Metformin attenuates plaque-associated tau pathology and reduces amyloid-beta burden in APP/PS1 mice

Chen, YX; Zhao, S; Fan, ZQ; Li, ZY; Zhu, YL; Shen, T; Li, KC; Yan, YP; Tian, J; Liu, ZR; Zhang, BR

Zhang, BR (corresponding author), Zhejiang Univ, Affiliated Hosp 2, Sch Med, Dept Neurol, Hangzhou, Peoples R China.

ALZHEIMERS RESEARCH & THERAPY, 2021; 13 (1):

Abstract

Background The neuropathological hallmarks of Alzheimer's disease (AD) are amyloid-beta (A beta) plaques and neurofibrillary tangles (NFTs). The amylo......

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