SLC19A1 transports immunoreactive cyclic dinucleotides

Luteijn, RD; Zaver, SA; Gowen, BG; Wyman, SK; Garelis, NE; Onia, L; McWhirter, SM; Katibah, GE; Corn, JE; Woodward, JJ; Raulet, DH

Raulet, DH (reprint author), Univ Calif Berkeley, Dept Mol & Cell Biol, 229 Stanley Hall, Berkeley, CA 94720 USA.; Raulet, DH (reprint author), Univ Calif Berkeley, Canc Res Lab, Div Immunol & Pathogenesis, Berkeley, CA 94720 USA.

NATURE, 2019; 573 (7774): 434

Abstract

The accumulation of DNA in the cytosol serves as a key immunostimulatory signal associated with infections, cancer and genomic damage(1,2). Cytosolic ......

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