Sensing Mitochondrial Acetyl-CoA to Tune Respiration

Mills, CA; Trub, AG; Hirschey, MD

Hirschey, MD (reprint author), Duke Univ, Med Ctr, Duke Mol Physiol Inst, Durham, NC 27701 USA.; Hirschey, MD (reprint author), Duke Univ, Med Ctr, Sarah W Stedman Nutr & Metab Ctr, Durham, NC 27701 USA.; Hirschey, MD (reprint author), Duke Univ, Med Ctr,

TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2019; 30 (1): 1

Abstract

Fatty acid synthesis (FAS) in mitochondria produces a key metabolite called lipoic acid. However, a new study by Van Vranken et al. [1] (Mol. Cell 201......

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