Stage-specific H3K9me3 occupancy ensures retrotransposon silencing in human pre-implantation embryos

Xu, RM; Li, S; Wu, Q; Li, C; Jiang, MX; Guo, L; Chen, M; Yang, LY; Dong, X; Wang, H; Wang, CF; Liu, XY; Ou, XH; Gao, SR

Liu, XY; Gao, SR (通讯作者)，Tongji Univ, Inst Regenerat Med, Shanghai East Hosp, Shanghai Key Lab Signaling & Dis Res,Sch Life Sci, Shanghai 200120, Peoples R China.;Ou, XH (通讯作者)，Guangdong Second Prov Gen Hosp, Guangdong Hong Kong Metab & Reprod Joint Lab, Guangzhou 510317, Peoples R China.;Gao, SR (通讯作者)，Tongji Univ, Clin & Translat Res Ctr, Shanghai Matern & Infant Hosp 1, Sch Life Sci & Technol, Shanghai 200092, Peoples R China.;Wang, CF (通讯作者)，Tongji Univ, Sch Life Sci & Technol, Tongji Hosp, D

CELL STEM CELL, 2022; 29 (7): 1051

Abstract

H3K9me3, as a hallmark of heterochromatin, is important for cell-fate specification. However, it remains un-known how H3K9me3 is reprogrammed during h......

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