USP47 deubiquitylates Groucho/TLE to promote Wnt-?-catenin signaling

Kassel, S; Hanson, AJ; Benchabane, H; Saito-Diaz, K; Cabel, CR; Goldsmith, L; Taha, M; Kanuganti, A; Ng, VH; Xu, G; Ye, F; Picker, J; Port, F; Boutros, M; Weiss, VL; Robbins, DJ; Thorne, CA; Ahmed, Y; Lee, E

Lee, E (通讯作者)，Vanderbilt Univ, Dept Cell & Dev Biol, Nashville, TN 37232 USA.;Ahmed, Y (通讯作者)，Dartmouth Coll, Dept Mol & Syst Biol, Geisel Sch Med, Hanover, NH 03755 USA.;Ahmed, Y (通讯作者)，Dartmouth Coll, Norris Cotton Canc Ctr, Geisel Sch Med, Hanover, NH 03755 USA.;Lee, E (通讯作者)，Vanderbilt Univ, Vanderbilt Ingram Canc Ctr, Sch Med, Nash, TN 37232 USA.

SCIENCE SIGNALING, 2023; 16 (771):

Abstract

The Wnt-beta-catenin signal transduction pathway is essential for embryonic development and adult tissue ho-meostasis. Wnt signaling converts TCF from......

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