The NFIA-ETO2 fusion blocks erythroid maturation and induces pure erythroid leukemia in cooperation with mutant TP53

Piqué-Borràs, MR; Jevtic, Z; Bagger, FO; Seguin, J; Sivalingam, R; Bezerra, MF; Louwagie, A; Juge, S; Nellas, I; Ivanek, R; Tzankov, A; Moll, UM; Cantillo, O; Schulz-Heddergott, R; Fagnan, A; Mercher, T; Schwaller, J

Schwaller, J (通讯作者),Univ Basel, Univ Childrens Hosp Basel, Dept Biomed, ZLF, Lab 202,Hebelstr 20, CH-4031 Basel, Switzerland.

BLOOD, 2023; 141 (18): 2245

Abstract

The NFIA-ETO2 fusion is the product of a t(1;16)(p31;q24) chromosomal translocation, so far, exclusively found in pediatric patients with pure erythro......

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