CRISPR/Cas9 screening using unique molecular identifiers

Schmierer, B; Botla, SK; Zhang, JL; Turunen, M; Kivioja, T; Taipale, J

Taipale, J (reprint author), Karolinska Inst, Dept Med Biochem & Biophys, Stockholm, Sweden.; Taipale, J (reprint author), Univ Helsinki, Genome Scale Biol Res Program, Fac Med, Helsinki, Finland.

MOLECULAR SYSTEMS BIOLOGY, 2017; 13 (10):

Abstract

Loss-of-function screening by CRISPR/Cas9 gene knockout with pooled, lentiviral guide libraries is a widely applicable method for systematic identific......

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