Identification of a C2 '-fluorinated SAH analogue

Labbe, MO; Li, FL; Chau, I; Xiong, ZJ; Santhakumar, V; Dostie, S; Guindon, Y

Dostie, S (corresponding author), Inst Rech Clin Montreal, Bioorgan Chem Lab, Montreal, PQ H2W 1R7, Canada.; Guindon, Y (corresponding author), Univ Montreal, Dept Chem, Montreal, PQ H3C 3J7, Canada.; Santhakumar, V (corresponding author), Univ Toronto, Struct Genom Consortium, Toronto, ON M5G 1L7, Canada.; Guindon, Y (corresponding author), Univ Ottawa, Dept Biochem Microbiol & Immunol, Ottawa, ON K1N 6N5, Canada.

CANADIAN JOURNAL OF CHEMISTRY, 2020; 98 (6): 318

Abstract

The progress towards the development of a nucleoside analogue with inhibitory properties against SETDB1, a histone methyltransferase (HMT), is describ......

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