T cell stimulation and expansion by SunTag-based clustering of anti-CD3/CD28 scFv

Zhong, KH; Liu, ZY; Li, HJ; Zhao, SS; Wang, YL; Guo, WH; Zheng, X; Yang, H; Guo, G; Zhou, LX; Xu, JG; Tong, AP

Tong, AP (corresponding author), Sichuan Univ, West China Med Sch, West China Hosp, State Key Lab Biotherapy & Canc Ctr, Chengdu, Sichuan, Peoples R China.; Xu, JG (corresponding author), Sichuan Univ, West China Hosp, Dept Neurosurg, Chengdu, Peoples R China.

AGING-US, 2020; 12 (11): 11061

Abstract

Therapeutic ex vivo T cell expansion is limited by low rates and poor functionality, especially for T cells from aged cancer patients. Here, we descri......

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