Minimal PAM specificity of a highly similar SpCas9 ortholog

Chatterjee, P; Jakimo, N; Jacobson, JM

Chatterjee, P (reprint author), MIT, Ctr Bits & Atoms, 77 Massachusetts Ave, Cambridge, MA 02139 USA.; Chatterjee, P (reprint author), MIT, Media Lab, 77 Massachusetts Ave, Cambridge, MA 02139 USA.

SCIENCE ADVANCES, 2018; 4 (10):

Abstract

RNA-guided DNA endonucleases of the CRISPR-Cas system are widely used for genome engineering and thus have numerous applications in a wide variety of ......

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