First-in-Humans Trial of Dasatinib-Derivative Tracer for Tumor Kinase-Targeted PET

Krebs, S; Veach, DR; Carter, LM; Grkovski, M; Fornier, M; Mauro, MJ; Voss, MH; Danila, DC; Burnazi, E; Null, M; Staton, K; Pressl, C; Beattie, BJ; Zanzonico, P; Weber, WA; Lyashchenko, SK; Lewis, JS; Larson, SM; Dunphy, MPS

Dunphy, MPS (corresponding author), Mem Sloan Kettering Canc Ctr, 1275 York Ave,Room S113E, New York, NY 10065 USA.

JOURNAL OF NUCLEAR MEDICINE, 2020; 61 (11): 1580

Abstract

We developed a first-of-kind dasatinib-derivative imaging agent, F-18-SKI-249380 (F-18-SKI), and validated its use for noninvasive in vivo tyrosine ki......

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