HDAC11 deficiency disrupts oncogene-induced hematopoiesis in myeloproliferative neoplasms

Yue, LZ; Sharma, V; Horvat, NP; Akuffo, AA; Beatty, MS; Murdun, C; Colin, C; Billington, JMR; Goodheart, WE; Sahakian, E; Zhang, L; Powers, JJ; Amin, NE; Lambert-Showers, QT; Darville, LN; Pinilla-Ibarz, J; Reuther, GW; Wright, KL; Conti, C; Lee, JY; Zheng, XZ; Ng, PY; Martin, MW; Marshall, CG; Koomen, JM; Levine, RL; Verma, A; Grimes, HL; Sotomayor, EM; Shao, ZH; Epling-Burnette, PK

Epling-Burnette, PK (corresponding author), H Lee Moffitt Canc Ctr & Res Inst, Dept Immunol, Tampa, FL 33612 USA.

BLOOD, 2020; 135 (3): 191

Abstract

Protein acetylation is an important contributor to cancer initiation. Histone deacetylase 6 (HDAC6) controls JAK2 translation and protein stability an......

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