Nuclear Imaging Study of the Pharmacodynamic Effects of Debio 1143, an Antagonist of Multiple Inhibitor of Apoptosis Proteins (IAPs), in a Triple-Negative Breast Cancer Model

Bellaye, PS; Oudot, A; Vrigneaud, JM; Raguin, O; Bichat, F; Vaslin, A; Maby-El Hajjami, H; Zanna, C; Vuagniaux, G; Fumoleau, P; Denat, F; Brunotte, F; Collin, B

Bellaye, PS (reprint author), Ctr Georges Francois Leclerc, Dijon, France.

CONTRAST MEDIA & MOLECULAR IMAGING, 2018; ():

Abstract

Background. Debio 1143, a potent orally available SMAC mimetic, targets inhibitors of apoptosis proteins (IAPs) members and is currently in clinical t......

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