Crosstown Traffic: Lymphodepleting Chemotherapy Drives CAR T Cells

Davies, DM; Maher, J

Maher, J (corresponding author), Kings Coll London, CAR Mech Lab, Sch Canc & Pharmaceut Sci, Guys Canc Ctr, London SE1 9RT, England.; Maher, J (corresponding author), Guys Hosp, Leucid Bio Ltd, London SE1 9RT, England.; Maher, J (corresponding author), Kings Coll Hosp NHS Fdn Trust, Dept Clin Immunol & Allergy, Denmark Hill, London SE5 9RS, England.; Maher, J (corresponding author), Eastbourne Hosp, Dept Immunol, Kings Dr, Eastbourne BN21 2UD, E Sussex, England.

CANCER CELL, 2021; 39 (2): 138

Abstract

CAR-engineered T cell immunotherapy has proven transformative in selected hematological malignancies. However, solid tumors largely remain impervious ......

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